Mild asymmetric lateral brain ventricles and the correlation to chronic

MILD ASYMMETRIC LATERAL BRAN VENTRICLES AND MIGRAINES 9

Mildasymmetric lateral brain ventricles and the correlation to chronicheadaches and migraines

Abstract

Amild asymmetric lateral brain ventricle is an intriguing condition inmedicine. Its impacts in the human body are not well understood(Kirogluet al, 2002). This study seeks to identify its correlation withheadaches and migraines. Some studies reveal that there is norelationship between migraines and headaches however, others confirmthat there is a high possibility that the two are related. Therelevance of asymmetric lateral brain ventricle is of greatsignificance with regard to headaches and migraines. The researchdesign was conducted in Highlands’s hospital in Connellsville where243 patients with no known brain history, but were suffering fromchronic headaches or migraines, participated. These patientsunderwent a CT scan and only 15.6 percent of the participants hadasymmetric lateral brain ventricle. This is an indicator thatasymmetrical lateral brain ventricle relates to migraines andheadaches. However, the research has its limitations and leaves a gapfor further research.

Asymmetryof the cerebral lateral ventricles is a typical finding in crosssectional imaging of brains (Grosman et al, 1990). The discovery ofasymmetry in the brain is usually intriguing and has drawn muchattention in the field of medicine. Although it is believed thatasymmetrical lateral ventricle lacks clear pathological grounds, anumber of studies stipulate that its existence is accompanied by someintriguing facts such as functional weaknesses and right or lefthandedness. Other studies claim that it can cause some mild impactsin the brain. Many studies have investigated the correlation ofasymmetrical lateral brain ventricles with diseases such as autismhowever, little research has been done to investigate itscorrelations with recurring headaches and migraines. There is stilla huge gap in the studies of asymmetry of the lateral ventricles andits relationship with headaches and migraines.

Thepurpose of this research study is to investigate the significance ofasymmetrical lateral brain ventricles in the occurrence of chronicand recurring headaches and migraines.

Literaturereview

Thebrain ventricle is a continuation of the spinal cord central canal(Anvekar,2011).&nbspAsone reaches of age, the cerebrospinal found in the ventricles tendsto increase. A normal brain ventricle is symmetrical and not dilated.The presence of mild asymmetry of the lateral ventricle has nopathological significance, although there is need to follow up forany symptoms. Mild asymmetry can be passed off as a typical anatomyvariation as long as it is not associated with intra ventricularabnormality. However, moderate and severe cases of asymmetry oflateral brain ventricle should not be overlooked. Many studies havebeen conducted in search of pathology or association of thiscondition. Even though there is no pathological evidence thatasymmetry of lateral brain ventricle is dangerous to the body, somestudies reveal that it causes several conditions such as dementia,seizure and recurring headaches (Schwedt&amp Dodick, 2009). It is worth noting that there is no known cause of asymmetry in thelateral brain ventricle.

Therelationship between asymmetrical lateral brain ventricles andmigraines or chronic headaches is not clearly understood. Somestudies reveal that there is a great relationship betweenasymmetrical lateral brain ventricles and headaches. On the otherhand, some found no relationship at all. Valencia el al (2002)conducted a study of 78 patients with recurring migraines andheadaches and found out that 30% of the patients suffered fromunruptured cerebral aneurysm, basilar impression, cysticercosis,inflammatory sinus disease, intracranial lipoma, arachnoid cyst,intracranial neoplasm, and empty sella. However, this does not meanthat asymmetry in the lateral brain ventricles has no relationship atall with headaches and migraines. Grosman et al (1990) conducted aresearch in which nineteen of the patients under the study showed ahigh correlation between recurring headaches and asymmetry lateralbrain ventricles.

Itis worth noting that migraines and recurring headaches are caused byvarying cerebral problems. Nowak and James (1989) revealed thatpatients suffering from hydrocephalus are at a high risk ofcontracting migraines and recurring headaches. In other researches,some factors that contribute to headaches have also been known tocontribute to asymmetry lateral brain ventricles. For instance, brainillnesses that come with headaches as the main symptom have also beenknown to contribute lateral brain ventricle (Piatt,2004).

Researchdesign

Thestudy took place in Highlands’s Hospital in Connellsville PA, whichtook place for a period of six months from July 1, 2013 to December31, 2013. The participants were 276 adults aged between 18 to 70years suffering from chronic headaches or migraines. Out of the 276participants, 113 were males and 163 were females. The selectedparticipants had no known history of alcoholism, dementia, headinjury, hydrocephalus, cerebral atrophy, hemorrhage, encephalitis,and interracial mass, all of which are great contributors of chronicheadaches and migraines. Patients with known brain disorder historyor other traumatic related problems were excluded from the study.This means that the patients had normal brain conditions so that theywould not affect the effectiveness of the results. The only patientsthat were allowed to participate had no known brain complicationshistory. On the other hand, the participants were only patients whowere diagnosed with recurring headaches or migraines.

Theparticipants were all scanned using a Toshiba Toshiba 32 slicescanner and scanned supine head first. The orbital-meatal line wasalso used as anatomical reference. The scanning used a similar slicethickness and an interval space of 3 times 3 millimeters to cover upfor the entire skull and brain. Linear measurements were taken on theright and the left of the lateral ventricles.

Resultsand discussion

Outof the 276 participants, 17 males and 26 females had mildasymmetrical lateral brain ventricles. This accounted for 15.6% ofthe total target population. Also intriguing is that 42 out of the 43participants had right lateral ventricle as the larger ventricle,while only one had the complete opposite. Although the side of theasymmetrical lateral ventricles did not matter with regard to itscorrelation with migraines or chronic headaches, it was clear that itdevelops more on the right than on the left. This leaves a gap forstudy on where the asymmetrical lateral ventricles occurs most andwhy.

Thestudy revealed that 15.6 % tested positive for the study. This doesnot confirm whether asymmetrical lateral ventricles are actuallyrelated to chronic headaches and migraines. However, the relevance ofthe mild asymmetrical lateral brain ventricle cannot be ignored. Theresults indicate that the 15.6 percent of the participants may havebeen suffering from migraines and headaches because they hadasymmetrical lateral brain. It can be concluded that indeed thiscondition of the brain can be a great contributor to migraines andchronic headaches.

Nonetheless,it should be noted that the population that tested positive for thestudy may have other conditions that may contribute to migraines andrecurring headaches. There is a possibility that the number of peoplewho had asymmetrical lateral brain ventricle had also otherconditions that the rest of the population had. There was no controlpopulation that could help in understanding the correlation better.This means that there is no pathological ground on whether the 15.6percent who had asymmetrical lateral brain ventricle could alsoexhibit the same conditions that caused headaches in other patients.This study leaves a gap for future studies in assessing whether thetwo have a correlation.

Itis also worth noting that some conditions in the brain that causesmigraines and recurring headaches may also contribute to asymmetriclateral brain ventricle (Thompson&amp Amedee, 2009). Thisimplies that the population with asymmetrical ventricle may haveacquired this condition from other factors that cause headaches. Assuch, it cannot be deducted whether the headaches were caused byasymmetrical lateral brain ventricle or whether it is the migrainesthat caused the condition.

Conclusion

Asymmetryin the lateral brain ventricle should not be overlooked. Although itis not pathological and lacks clinical significance, the study foundthat it can cause migraines or recurring headaches. The 15.6percentage of people with asymmetrical lateral ventricle shows thatthere is a huge possibility that it can cause migraines andheadaches. Despite the limitations of the research, asymmetry in thelateral ventricle can be a major cause of several problems includingheadaches (Greenwood,2002). Theresearch is a basis for future studies on asymmetry of the lateralventricle and how it relates to chronic headaches or migraines.

References

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Greenwood,R. (2002). Head injury for neurologists.&nbspJournalOf Neurology, Neurosurgery &amp Psychiatry,73 (suppl 1), pp. 8–16.

Grosman,H., Stein, M., Perrin, R., Gray, R. &amp St Louis, E. (1990).Computed tomography and lateral ventricular asymmetry: clinical andbrain structural correlates.&nbspCanadianAssociation Of Radiologists Journal= Journal L`associationCanadienneDes Radiologistes,41 (6), p. 342.

Kiroglu,Y., Karabulut, N., Oncel, C., Yagci, B., Sabir, N. &ampOzdemir, B.(2008). Cerebral lateral ventricular asymmetry on ct: how muchasymmetry is representing pathology?.&nbspSurgicalAnd Radiologic Anatomy,30 (3), pp. 249–255.

Nowak,T. P. &amp James, H. E. (1989). Migraine headaches in hydrocephalicchildren: a diagnostic dilemma.&nbspChild`sNervous System,5 (5), pp. 310–314.

Piatt,J. (2004). Recognizing neurological conditions in pediatrician`soffice.&nbspPediatrClinN Am,51 pp. 237-270.

Schwedt,T. J. &ampDodick, D. W. (2009). Advanced neuroimaging ofmigraine.&nbspTheLancet Neurology,8 (6), pp. 560–568.

Schwedt,T. J. &ampDodick, D. W. (2009). Advanced neuroimaging ofmigraine.&nbspTheLancet Neurology,8 (6), pp. 560–568.

Thompson,T. L. &ampAmedee, R. (2009). Vertigo: a review of common peripheraland central vestibular disorders.&nbspJournalInformation,9 (1).

Valencia,M. M., Valencia, L. P. A. A. &ampMenezes, T. L. (2002).Computedtomography scan of the head in patients with migraine or tension-typeheadache.&nbspArquivosDe Neuro-Psiquiatria,60 (3A), pp. 542–547.