Microbiology Lab

Microbiology Lab


Thethree main species of Staphylococci include Saureus, S saprophiticusand Sepidermidis.In addition other species include Slugdunensis, S haemolyticus, S warneri, S schleiferi, S intermediuswhich are however, infrequent pathogens. Saureusexpresses more potential virulence factors this is because it iscategorized as more coagulase positive as compared to other specieslike Sepidrmidis.Some of the factors that denotes pathogenesis include 1) surfaceprotein that promote colonization of the hosts’ tissues, 2) thosefactors that inhibit phagocytosis and 3) toxins that cause diseasesyndrome by damaging host tissues. Above all this Staphylococcus mustbe coagulase positive (Sibal, Lin &amp Jogia, 2013).

“Spreadingfactors” is a descriptive word that is used to refer to a certainfamily of bacterial enzymes that work in order to affect the physicalproperties of body tissues. Hence promoting or enhancing pathogenpenetration. Hyaluronidaseis the original spreading factor which is produced by streptococci,staphylococci and clostridia. The enzyme is responsible for attackingthe interstitial cement that acts a connectivity tissue bydepolymerizing hyaluronic acid. Other spreading factors includecollagenase (produced by clostridiumhistolyticum and clostridium perfringens),Neuraminidase(produced by intestinal pthogenslikeVibriocholera and shigella dysenteriae),streptokinase and staphylokinase(streptococci and staphylococci).

Thetwo main spreading agents used by staphylococci are staphlokinaseand Hyaluronidasewhich is termed as an original spreading factor. Saureuscauses a number of complications to the body and some of the sidefactors of the pathogenesis include skin lesions, deep seatedinfections, and hospital acquired surgical wounds among othercomplications (Lämmler, 2014). On the other hand Sepidrmidisis responsible for infections that arise from in dwelling medicaldevices. Ssaprophiticuscauses urinary tract infections especially when it comes to girls.


Lämmler,C. (2014). Comparative Studies on Bacteriolytic Properties ofStaphylococcus chromogenes and Staphylococcus hyicus. JournalOf Veterinary Medicine, Series B,38(1-10),468-472. doi:10.1111/j.1439-0450.1991.tb00897.x

Sibal,A., Lin, Z., &amp Jogia, D. (2013). Coagulase-negativestaphylococcus endocarditis: staphylococcus lugdunensis. AsianCardiovascular And Thoracic Annals,19(6),414-415. doi:10.1177/0218492311419764